Abstract: Objective :To review the diagnosis and surgical treatment of primary cardiac tumors. Methods :The clinical features and surgical results in 127 patients of primary cardiac tumors were analyzed retrospectively. Results :Between September 1988 and January 2004, one hundred and twenty-seven patients with primary cardiac tumors underwent surgical treatment by the aid of general anesthesia and cardiopulmonary bypass, comprising 2.48%(127/5128) of all open-heart operation. Forty-four patients were male and 83 female. Age ranged from 10 months 72 years old (mean standard 39.89 16.75years). The perioperative mortality was 8.66%(11/127). The mortality of benign tumors and malignant tumors was 6.03% and 37.5% respectively. The difference between them was significant (P<0.05).One hundred and sixteen patients were discharged from hospital and 97 cases were followed-up for 3months 15.3 years. Eight patients with myxoma recurred 13 times. The mean recurrence time was (4.77±4.57) years. Conclusions :The clinical findings of primary cardiac tumor are diverse and tomAlex. The echocardiography is particular and predominant for the diagnosis, and the surgical treatment is the first choice. The prognosis of the cardiac tumors is mainly determined by the histopathological type and whether they grow multicentrically.